Mohs Newsletter Week of May 20, 2025

🔍 AI Achieves 99.26% Accuracy in Endometrial Cancer Detection

A groundbreaking AI model named ECgMLP, developed by Charles Darwin University and global research partners, has reached 99.26% accuracy in diagnosing endometrial cancer from histopathological images—outperforming previous models. It also demonstrated over 98% accuracy for breast, colorectal, and oral cancers.

Read more – CDU Researchers

🩺 Mohs Surgery Outperforms Wide Local Excision in High-Stage cSCC

A multicenter validation study confirms that Mohs micrographic surgery (MMS) offers superior local control and lower recurrence rates compared to wide local excision (WLE) in treating high-stage cutaneous squamous cell carcinoma (cSCC).

Read more - PubMed

Read more - JNCCN 360

🔬 Advancements in Histopathology Imaging

New compact metasurface polarimeters allow for high-accuracy polarization imaging, streamlining structural tissue diagnostics in histopathology.

Read more - Study – arXiv

🎧 Podcast Pick:

Citología Ciencia y Arte

This Spanish-language podcast offers engaging expert interviews and insights into cytology and histotechnology.

Listen on: Spotify | Apple Podcasts

✨ Mohs Lab Spotlight: Adapting to Staining Systems with Precision

At MohsPro, manual staining is preferred for its speed and consistency when well-managed. However, automated staining systems are helpful in:

• Training labs, where techs are developing workflow control
• High-volume settings, allowing lead techs to continue sectioning

MohsPro techs are trained to adapt and deliver excellence in any lab setup.

⚡ Troubleshooting Tip (Histopathology): Tissue Lifting Off Slides?

To reduce lifting in routine histopathology workflows:

• Pre-warm your slides
• Ensure tissue blocks are not over-hydrated
• Dip slides in 95% alcohol and air dry before staining

Note: This tip is not applicable to Mohs frozen section protocols.

⚡ Mohs Tech Tips from MohsPro Leaders

Avoid pre-chilling specimen chucks. Pre-chilling can prevent embedding media from properly settling into chuck grooves, reducing adherence and risking section instability.

📅 Upcoming Event

ASMH 2025 Annual Meeting

Location: Chicago, IL
Dates: June 6–8

Details:  https://www.asmh.org/

Stay informed on the latest advancements, lab tips, and global updates in Mohs surgery and histopathology by visiting www.mohsnews.com on a weekly basis. For more detailed information and resources, visit our website at www.mohspro.com. We are #theoriginalmohspros.