Mohs & Histopathology Insights – July 2025

🔬 Scancell Launches UK Vaccine Trial for Advanced Melanoma†

The UK’s NHS is partnering with biotech firm Scancell to run clinical trials of a DNA vaccine designed for advanced melanoma—particularly in patients unresponsive to immunotherapy. These “off the shelf” vaccines may become a cost-effective alternative to personalized treatments. Enrollment is planned to begin by October 2025.

🔗 Source: Financial Times‍

🩻 Burnout & Social Determinants Impact Dermatology Outcomes†

A 2025 AAD session highlighted how factors like economic hardship, access barriers, and education influence skin cancer outcomes. Dr. Rebecca Vasquez, FAAD, emphasized cases where providing free care significantly improved outcomes among underserved patients.

🔗 Source: AAD / Managed Healthcare Executive

🧑‍⚕️ Dr. Lindsey Zubritsky: Educating via Social Media for Dermatologists

At AAD 2025, Dr. Zubritsky (“the derm guru”) shared her strategy for building a meaningful social presence across TikTok and Instagram. With over 3 million followers, she uses batch content creation and strategic posts to fight misinformation and highlight dermatology expertise.

🔗 Source: Modern Aesthetics

🧪 Mohs Topic: Immunotherapy Education for Skin Cancer

A new CME course targets Mohs surgeons and dermatologists treating advanced basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC). It offers risk assessment and integration of systemic immunotherapies into a multidisciplinary care model.

🔗 Source: ACMS / Med Learning Group

🎧 Podcast Pick: The Future of Dermatology

Hosted by Dr. Faranak Kamangar, this podcast continues to explore cutting-edge topics—this month’s focus includes psoriasis management and eczema breakthroughs.

🔗 Listen on Podbean

🧠 Innovation Spotlight: PARS Virtual Histology Matching H&E

A new study finds Photon Absorption Remote Sensing (PARS) yields virtual H&E images that reach > 95% diagnostic agreement with conventional staining. Dermatopathologists could not reliably tell PARS apart from standard H&E, and confidence levels were equivalent.

🔗 Source: arXiv arxiv.org

🌴 Florida News Spotlight

• Florida Dermatology Specialists celebrates its first anniversary, having completed over 1,000 Mohs surgeries in its inaugural year—led by fellowship-trained Dr. Richard Krathen.
  🔗 Practice blog update
• Mobile Mohs Screening: OnSpot Dermatology launched scout clinics in Palm Beach, offering on site skin cancer screenings and minor Mohs procedures to underserved populations. Result: earlier detection and fewer referral delays.
  🔗 Local news coverage – CBS12 Palm Beach
• Mohs Lab Spotlight: Integrating AI for Enhanced Diagnostic Accuracy
• A Florida Mohs lab recently adopted an AI-assisted margin-detection tool, improving both intraoperative precision and process efficiency—demonstrating tangible benefits of integrating AI workflows in routine practice.
  

⚡ Troubleshooting Tip (Mohs & Histopathology): Optimizing Fresh Tissue Transport

• Mohs Techs: Keep freshly excised tissue in chilled saline—not frozen—to prevent freeze artifacts before processing.
• Histopathology: Minimize delays in fixation by starting formalin immersion within five minutes of excision to preserve nucleic and cellular architecture.
  Both: Temperature control before processing is critical to tissue integrity.

Stay informed on the latest advancements, lab tips, and global updates in Mohs surgery and histopathology by visiting www.mohsnews.com monthly. For more detailed information and resources, visit www.mohspro.com. We are #theoriginalmohspros.